VOLVEFIX-O TABLETS: Comprehensive Overview

Introduction

VOLVEFIX-O TABLETS are a combination antibiotic formulation that contains Cefixime 200 mg and Ofloxacin 200 mg as the active ingredients. These two antibiotics work synergistically to treat a wide range of bacterial infections by targeting the bacteria at different sites of action. Cefixime is a third-generation cephalosporin antibiotic, while Ofloxacin is a fluoroquinolone antibiotic. Together, they provide broad-spectrum coverage against both Gram-positive and Gram-negative bacteria, making VOLVEFIX-O TABLETS an effective treatment for various infections.

Composition

• Cefixime 200 mg
• Ofloxacin 200 mg

How VOLVEFIX-O TABLETS Work

• Cefixime is a broad-spectrum antibiotic that works by inhibiting bacterial cell wall synthesis. It binds to penicillin-binding proteins (PBPs) on the bacterial cell wall, preventing the synthesis of peptidoglycan, a vital component of the cell wall. Without a strong cell wall, the bacteria are unable to survive, leading to bacterial cell death.

• Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are crucial enzymes for DNA replication. By preventing these enzymes from functioning, Ofloxacin interferes with bacterial DNA replication and cell division, leading to bacterial death.

This combination of Cefixime and Ofloxacin in VOLVEFIX-O TABLETS makes it highly effective in treating infections caused by a wide range of pathogens, including those resistant to other antibiotics.

Indications for Use

VOLVEFIX-O TABLETS are commonly used to treat a variety of bacterial infections, including:

1. Respiratory Tract Infections:

   • Pneumonia, bronchitis, and sinusitis caused by susceptible bacteria.
   • Pharyngitis and tonsillitis.

2. Urinary Tract Infections (UTIs):

   • Cystitis (bladder infections) and pyelonephritis (kidney infections).

3. Skin and Soft Tissue Infections:

   • Cellulitis, impetigo, and other skin infections caused by sensitive bacteria.

4. Gastrointestinal Infections:

   • Infections like enteritis caused by Salmonella or Shigella bacteria.

5. Sexually Transmitted Infections (STIs):

   • Gonorrhea, a common sexually transmitted infection, is effectively treated with this combination of antibiotics.

Dosage and Administration

The typical adult dosage of VOLVEFIX-O TABLETS is:

• For most infections: One tablet (200 mg Cefixime + 200 mg Ofloxacin) twice daily.
• For severe infections: The dosage may be adjusted according to the severity and the patient’s response to the medication.

For pediatric patients, the dosage is typically based on the child’s weight and the severity of the infection. It’s important to take the tablets as prescribed by your healthcare provider, and the full course of antibiotics should always be completed, even if symptoms improve before the treatment is finished.

VOLVEFIX-O TABLETS can be taken with or without food. It is recommended to drink a full glass of water when taking the tablet to help with its absorption and minimize any potential stomach discomfort.

Side Effects of VOLVEFIX-O TABLETS

As with any medication, VOLVEFIX-O TABLETS may cause side effects, although not everyone will experience them. The common side effects include:

• Gastrointestinal disturbances: Nausea, vomiting, diarrhea, abdominal pain.
• Headache or dizziness.
• Skin reactions: Rash, itching, or swelling.
• Changes in taste or dry mouth.

In rare cases, more serious side effects may occur, including:

• Severe allergic reactions: Symptoms such as swelling of the face, lips, tongue, or throat, difficulty breathing, and severe rash.
• Clostridioides difficile-associated diarrhea: A potentially life-threatening condition that causes severe abdominal pain and diarrhea.
• Liver dysfunction: Yellowing of the skin or eyes (jaundice), dark urine, or unusual fatigue could indicate liver issues.
• Tendon rupture or joint pain: This is a rare but serious side effect associated with Ofloxacin, especially in elderly patients or those taking corticosteroids.

If you experience any of these serious side effects, it is essential to contact your healthcare provider immediately.

Precautions and Warnings

Before taking VOLVEFIX-O TABLETS, inform your healthcare provider if you:

• Have a history of allergic reactions to Cefixime, Ofloxacin, or other antibiotics.
• Have liver disease, kidney disease, or any gastrointestinal disorders, as the dosage may need to be adjusted.
• Are pregnant or planning to become pregnant, or if you are breastfeeding. Although this combination of antibiotics is generally considered safe during pregnancy, it should only be used if absolutely necessary.
• Are taking any other medications, including over-the-counter drugs and supplements. Some medications may interact with Cefixime or Ofloxacin and affect the effectiveness of the treatment.

Drug Interactions

VOLVEFIX-O TABLETS may interact with certain medications, such as:

• Antacids: Antacids containing aluminum or magnesium may decrease the absorption of Ofloxacin, reducing its effectiveness.
• Anticoagulants (e.g., warfarin): The anticoagulant effects may be enhanced when taking Ofloxacin, leading to an increased risk of bleeding.
• Other antibiotics: Certain antibiotics, such as erythromycin, may interact with Cefixime and affect the antibiotic’s action.
• Corticosteroids: The risk of tendon rupture may increase when Ofloxacin is used in combination with corticosteroids.

Always inform your healthcare provider about any medications you are currently taking, including over-the-counter drugs.

Storage Instructions

• Storage: Store VOLVEFIX-O TABLETS at room temperature, away from moisture, heat, and direct sunlight.
• Keep out of reach of children: Ensure that the medication is stored securely and out of children’s reach to avoid accidental ingestion.
• Expiration: Do not use VOLVEFIX-O TABLETS after the expiration date printed on the packaging.

Contact Us

For more information about VOLVEFIX-O TABLETS or if you have any questions regarding the medication, please feel free to contact us with Osiante biotech and Chemo biological

Our team is available to assist with inquiries, provide additional information, and guide you on our PCD Pharma Franchise opportunities for distributing high-quality pharmaceutical products like VOLVEFIX-O TABLETS.

Conclusion

VOLVEFIX-O TABLETS are a potent and effective combination of Cefixime 200 mg and Ofloxacin 200 mg, designed to treat a broad range of bacterial infections. This dual-action formulation not only helps eliminate infection but also provides a comprehensive solution to prevent bacterial resistance.

By following the prescribed dosage and completing the full course of treatment, patients can achieve the best therapeutic outcomes. Always consult your healthcare provider before starting any new medication and inform them about any underlying conditions or medications you are currently taking